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| The following information (Health Effects, Handling/Disposal, and Ingredients) is taken from the product label and/or the Material Safety Data Sheet (MSDS) prepared by the manufacturer. The National Library of Medicine does not test products nor does it evaluate information from the product label or the MSDS. (What is an MSDS?)
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Health Effects
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From MSDS
IMMEDIATE CONCERNS:
AVOID CONTACT WITH EYES, SKIN OR CLOTHING
AVOID BREATHING VAPOR OR SPRAY MIST
KEEP OUT OF REACH OF CHILDREN
POTENTIAL HEALTH EFFECTS
EYES: This substance is not expected to cause prolonged or significant eye irritation.
SKIN: This substance is not expected to cause prolonged or significant skin irritation. If absorbed through the skin, this substance is considered practically non-toxic to internal organs.
INGESTION: The systemic toxicity of this substance has not been determined. However, it should be practically non-toxic to internal organs if swallowed.
INHALATION: The systemic toxicity of this substance has not been determined. However, it should be practically non-toxic to internal organs if inhaled.
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From MSDS
Chlorpyrifos is an inhibitor of the cholinesterase enzyme, found in nervous tissue, red blood cells, and plasma.
COMMENTS HEALTH: Depending upon the extent and degree of overexposure to the product, signs and symptoms of cholinesterase inhibition can result following either ingestion, skin contact or inhalation routes of exposure. Signs and symptoms of cholinesterase inhibition can result from either acute (one time), subchronic (repeated short-term) and chronic (daily life-time) overexposure to the product.
Signs and symptoms of cholinesterase inhibition usually occur within 12 hours following overexposure. These effects may include, but may not be limited to, headache, dizziness, weakness, nausea, vomiting, diarrhea, constriction of the pupil of the eye, blurred or dark vision, excessive salivation or nasal discharge, profuse sweating and abdominal cramps. Incontinence, unconsciousness, convulsions and breathing difficulties are indicative of severe poisoning. In untreated severe poisoning, death is due to respiratory failure or cardiac arrest.
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From MSDS
Chlorpyrifos was not carcinogenic when tested in rats and mice in two-year feeding studies.
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From MSDS
EYES: Hold eye open and rinse slowly and gently with water for 15 to 20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eyes. Call a poison control center or doctor for treatment advice.
SKIN: If on skin or clothing, take off contaminated clothing. Rinse skin immediately with plenty of water for 15 to 20 minutes. Call a poison control center or doctor for treatment advice.
INGESTION: If swallowed, call a poison control center or doctor immediately for treatment advice. Have person sip glass of water if able to swallow. Do not induce vomiting unless told to by a poison control center or doctor. Never give anything by mouth to an unconscious person.
INHALATION: Move person to fresh air. If person is not breathing, call 911 or an ambulance, then give artificial respiration, preferably by mouth-to-mouth, if possible. Call a poison control center or doctor for further treatment advice.
NOTES TO PHYSICIAN: This material contains a cholinesterase inhibitor.
Measurement of blood cholinesterase activity may be useful in monitoring exposure. If signs and/or symptoms of cholinesterase inhibition appear, atropine sulfate is antidotal. 2-PAM (PROTOPAM) is also antidotal and may be used in conjunction with atropine but should not be used alone.
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0 = Minimal; 1 = Slight; 2 = Moderate; 3 = Serious; 4 = Severe;
N = No information provided by manufacturer; * = Chronic Health Hazard |
| 2001-06-26 |
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Handling/Disposal
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From MSDS
GENERAL PROCEDURES: Keep pesticide in original container. For containers larger then 24 oz.: Place sprayer nozzle under handle on container so the sprayer is not below level of contents of container to prevent leakage. Store in a secure, preferably locked, storage area. Protect container from freezing.
STORAGE TEMPERATURE: Do not store below 32
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From MSDS
If necessary to dispose of partially filled product container, securely wrap it in several layers of newspaper and discard in trash.
EMPTY CONTAINER: Do not reuse container. Rinse thoroughly before discarding in trash.
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Ingredients from MSDS/Label
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| Chemical | CAS No / Unique ID | Percent |
| Chlorpyrifos | 002921-88-2 | 0.5 |
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